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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP4R4
All Species:
22.42
Human Site:
Y627
Identified Species:
49.33
UniProt:
Q6NUP7
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NUP7
NP_066009.2
873
99452
Y627
N
V
R
M
K
L
C
Y
L
L
P
K
V
K
S
Chimpanzee
Pan troglodytes
XP_522937
1109
124026
Y863
N
V
R
M
K
L
C
Y
L
L
P
K
V
K
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_547959
916
103055
Y677
N
V
R
M
K
L
C
Y
L
L
P
K
V
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0Y0
875
99462
Y629
N
V
R
M
K
L
C
Y
L
L
P
K
V
K
S
Rat
Rattus norvegicus
NP_001128104
821
93759
L609
D
M
H
L
L
Q
Q
L
E
M
C
V
R
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511225
842
94937
H615
N
V
R
M
K
L
C
H
L
L
P
K
V
K
S
Chicken
Gallus gallus
XP_421339
873
99507
Y627
N
V
R
I
K
L
C
Y
L
L
P
K
V
K
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_696336
875
98944
Y630
N
V
R
Y
K
L
C
Y
M
L
P
K
L
R
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393531
722
82259
V518
N
I
K
P
A
Q
R
V
E
L
R
T
K
L
C
Nematode Worm
Caenorhab. elegans
NP_495884
986
111167
K681
N
I
R
I
R
A
I
K
F
L
P
K
I
K
S
Sea Urchin
Strong. purpuratus
XP_781974
792
88319
V588
M
D
L
T
A
D
P
V
P
N
I
R
L
K
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.1
N.A.
88.3
N.A.
90.7
83.8
N.A.
65.2
79.8
N.A.
59.2
N.A.
N.A.
31.2
23.2
40.8
Protein Similarity:
100
78
N.A.
90.5
N.A.
95
88.5
N.A.
78.4
91.1
N.A.
77.1
N.A.
N.A.
49.8
45.5
60.9
P-Site Identity:
100
100
N.A.
100
N.A.
100
6.6
N.A.
93.3
93.3
N.A.
73.3
N.A.
N.A.
13.3
46.6
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
33.3
N.A.
100
100
N.A.
93.3
N.A.
N.A.
26.6
73.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
19
10
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
64
0
0
0
10
0
0
0
10
% C
% Asp:
10
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
19
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
19
0
19
0
0
10
0
0
0
10
0
10
0
0
% I
% Lys:
0
0
10
0
64
0
0
10
0
0
0
73
10
82
0
% K
% Leu:
0
0
10
10
10
64
0
10
55
82
0
0
19
10
10
% L
% Met:
10
10
0
46
0
0
0
0
10
10
0
0
0
0
10
% M
% Asn:
82
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
0
10
0
10
0
73
0
0
0
0
% P
% Gln:
0
0
0
0
0
19
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
73
0
10
0
10
0
0
0
10
10
10
10
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
73
% S
% Thr:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% T
% Val:
0
64
0
0
0
0
0
19
0
0
0
10
55
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
55
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _